The Macromolecular Structure Group (MSG) is part of the Department of Biochemistry and Biophysics in the School of Medicine at the University of California, San Francisco.
MISSION
The lab focuses on understanding the molecular mechanisms of certain key biological processes, as well as signal transduction between processes at the level of protein structure, dynamics, and mechanism. Molecular cloning, expression, site-directed mutagenesis, and strong focus onto biochemistry are a key part of the arsenal for defining molecular mechanisms. The aim is to concentrate on the questions of how signals cross membranes, and how membrane proteins, and membrane channels work at the level of atomic structure. Also, on how the signal recognition particle (SRP) directs membrane and secreted proteins to the membrane.
Research
The Stroud Lab is researching a variety of topics to help understand molecular mechanisms of certain key biological processes. To find out more about what specifically the lab is seeking to understand, please visit the lab's website below.
Professor | Biochemistry & Biophysics | Pharmaceutical Chemistry, UCSF
The MSG focuses on the study of macromolecular structure, function, and interactions through the varied research tools of biochemistry and biophysics, including X-ray Crystallography and SAXS, Electron & Light Microscopy, NMR, Mass Spectrometry, and Molecular Biology.